See all 7042 hotels in James Island
- Clean, Private Guesthouse-9 min. to Downtown Charleston, 15 min. to FollyBeach!
- Island Retreat - Great for Large Groups
- Cozy Island Cottage S
- The Francis Marion Hotel
- Hotel Indigo Mount Pleasant by IHG
- The Ryder Hotel
- Harborside at Charleston Harbor Resort and Marina
- Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG
- Emeline
- La Quinta Inn & Suites by Wyndham Charleston Riverview
- Cambria Hotel Mount Pleasant – Charleston
- The Beach Club at Charleston Harbor Resort and Marina
- Mills House Charleston, Curio Collection by Hilton
- The Vendue
- Tides Folly Beach, Charleston's Oceanfront Hotel
- The Palmetto Hotel
- Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
- Hotel Bennett
- Embassy Suites by Hilton Charleston Historic District
- Andrew Pinckney Inn
- Planters Inn
- TownePlace Suites by Marriott Charleston-North Charleston
- The Charleston Place
- Drury Plaza Hotel North Charleston
- Courtyard by Marriott Charleston-North Charleston
- SpringHill Suites by Marriott Charleston N./Ashley Phosphate
- Hyatt Place North Charleston
- The Palms Oceanfront Hotel
- Tru by Hilton Charleston Airport
- The Restoration
- HarbourView Inn
- DoubleTree by Hilton Hotel & Suites Charleston Airport
- The Sanctuary at Kiawah Island Golf Resort
- Indigo Inn
- TownePlace Suites by Marriott Charleston-West Ashley
- Hyatt Place Charleston Airport/Convention Center
- Staybridge Suites Charleston - Mount Pleasant by IHG
- DoubleTree by Hilton Charleston Mount Pleasant
- Hilton Garden Inn Charleston / Mt. Pleasant
- North Charleston Lodge
- The Nickel Hotel
- Church Street Inn Historic Charleston, Ascend Collection Hotel
- Shem Creek Inn
- Best Western Airport Inn & Suites
- The Loutrel
- Comfort Suites at Isle Of Palms Connector
- Aloft Charleston Airport & Convention Center
- Holiday Inn Charleston Riverview by IHG
- Charleston Creekside Inn
- Hilton Garden Inn Charleston Waterfront/Downtown
- Seaside Inn Oceanfront
- Hampton Inn & Suites Charleston Airport
- Town & Country Inn and Suites
- Holiday Inn Express & Suites Charleston Arpt-Conv Ctr Area
- Springhill Suites by Marriott Charleston Mount Pleasant
- Hyatt Place Mount Pleasant Towne Centre
- Home2 Suites by Hilton North Charleston-University Blvd
- DoubleTree by Hilton Charleston Riverview
- Embassy Suites by Hilton Charleston Airport Convention Ctr
- Charleston Marriott
- Hampton Inn Charleston - Daniel Island
- Comfort Inn & Suites Charleston Airport Convention Center
- The Spectator Hotel
- Courtyard by Marriott North Charleston Airport/Coliseum
- Fairfield Inn & Suites by Marriott Charleston Airport/Conven
- Residence Inn Charleston North/Ashley Phosphate
- Holiday Inn Express & Suites Mt. Pleasant by IHG
- Best Western Charleston Inn
- French Quarter Inn
- Comfort Inn & Suites Patriots Point
- Fairfield Inn & Suites Charleston North/Ashley Phosphate
- Comfort Suites Charleston West Ashley
- Hotel Richemont
- Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
- Hawthorn Suites by Wyndham North Charleston, SC
- Home2 Suites By Hilton Mt Pleasant Charleston
- Crowne Plaza Charleston Airport - Conv Ctr by IHG
- Tru by Hilton Charleston Ashley Phosphate
- Hyatt House Charleston / Mount Pleasant
- Home2 Suites by Hilton Charleston Daniel Island
- WoodSpring Suites North Charleston Airport I-526
- Courtyard by Marriott Charleston Mount Pleasant
- The Dunlin, Auberge Collection