See all 18525 hotels in Historic Route 66
- Hyatt Regency Chicago
- Best Western Grant Park Hotel
- Swissotel - Chicago
- Silversmith Hotel Chicago Downtown
- Trump International Hotel & Tower Chicago
- The Royal Sonesta Chicago River North
- Courtyard by Marriott Chicago Magnificent Mile
- Embassy Suites by Hilton Chicago Downtown Magnificent Mile
- Hilton Chicago
- Golden Nugget Laughlin
- The Godfrey Hotel Chicago
- Hilton Chicago/Magnificent Mile Suites
- Hollywood Casino & Hotel St. Louis
- Don Laughlin's Riverside Resort Hotel & Casino
- Avi Resort & Casino
- Hyatt Regency St. Louis at The Arch
- Sofitel Chicago Magnificent Mile
- Travelodge by Wyndham Downtown Chicago
- The Chicago Hotel Collection - Magnificent Mile
- Sable at Navy Pier Chicago, Curio Collection by Hilton
- Sheraton Grand Chicago Riverwalk
- The Allegro Royal Sonesta Hotel Chicago Loop
- 21c Museum Hotel Chicago
- Hampton Inn Chicago-O'Hare International Airport
- The Langham, Chicago
- Hotel Saint Clair- Magnificent Mile
- Hyatt Place Chicago/O'Hare Airport
- Hampton Inn Chicago Downtown/Magnificent Mile
- Hyatt Regency McCormick Place Chicago
- Hilton Garden Inn Chicago Downtown South Loop
- Kinzie Hotel
- Pear Tree Inn St. Louis Airport
- Red Roof Inn PLUS+ Chicago - Willowbrook
- Hyatt Centric Chicago Magnificent Mile
- Hotel Aspen InnSuites Flagstaff/Grand Canyon
- Tropicana Laughlin
- Hotel Chicago West Loop
- The Last Hotel
- SpringHill Suites Chicago O'Hare by Marriott
- River Spirit Casino Resort
- Hyatt Regency Tulsa Downtown
- Hotel Chicago Downtown, Autograph Collection by Marriott
- Millennium Knickerbocker Chicago
- Greenstay Hotel & Suites
- Loews Chicago O'Hare Hotel