See all 852 hotels in Defiance
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- The Wildwood Hotel
- Ameristar Casino Resort and Spa
- Hollywood Casino & Hotel St. Louis
- Country Inn & Suites by Radisson, St. Charles Historic District
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Drury Plaza Hotel St. Louis St. Charles
- Drury Inn & Suites Southwest St. Louis
- Drury Plaza Hotel St. Louis Chesterfield
- Hilton St. Louis Frontenac
- Drury Inn & Suites St. Louis St. Peters
- Comfort Suites St Charles - St Louis
- Hampton Inn St. Charles St. Peters
- Fairfield Inn & Suites by Marriott St. Louis Chesterfield
- Drury Plaza Hotel St. Louis Creve Coeur
- Hampton Inn & Suites St. Charles Old Town Area
- Crowne Plaza St. Louis Airport by IHG
- Extended Stay America Suites St Louis St Peters
- Hyatt Place St. Louis/Chesterfield
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Best Western Plus The Charles Hotel
- Hilton Garden Inn Chesterfield
- Staybridge Suites St Louis - Westport by IHG
- Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
- Courtyard by Marriott St. Louis Chesterfield
- Courtyard by Marriott St Louis Westport Plaza
- Holiday Inn St. Louis West Six Flags by IHG
- Courtyard by Marriott St. Louis St. Peters
- DoubleTree by Hilton Hotel St. Louis - Chesterfield
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hampton Inn St. Louis Wentzville
- Quality Inn
- Hampton Inn St. Louis/Chesterfield
- Baymont by Wyndham Warrenton
- Marriott St. Louis West
- Fairfield Inn & Suites St Louis Westport
- WoodSpring Suites St Peters-OFallon
- Hampton Inn & Suites St. Louis/Chesterfield
- Country Inn & Suites by Radisson, St. Peters, MO
- Sheraton Westport Plaza Hotel St. Louis
- Comfort Inn St. Louis Airport
- Super 8 by Wyndham St Charles
- Super 8 by Wyndham Warrenton
- Holiday Inn St. Louis Arpt West-Earth City by IHG
- Homewood Suites by Hilton St. Louis-Chesterfield
- Hilton Garden Inn St. Louis/O'Fallon MO
- Extended Stay America Select Suites - St. Louis - Airport - Central
- TownePlace Suites by Marriott Wentzville
- Residence Inn by Marriott St. Louis West County
- Motel 6 Maryland Heights, MO
- Hampton Inn St. Louis/Westport
- Embassy Suites by Hilton St. Louis Airport
- Super 8 by Wyndham Eureka/Six Flags Nearby
- Holiday Inn Express Warrenton by IHG
- Quality Inn Near Six Flags St. Louis
- Residence Inn by Marriott O'Fallon