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Lowest round trip fares by airline from Des Moines and Panama City
Cheapest prices ($183 One Way, $360 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Great Deals On Cheap Hotels in Panama City
Boardwalk Beach Hotel
Reviewed on Nov 22, 2024
Casa Loma Inn
Reviewed on Nov 26, 2024
Ramada by Wyndham Panama City Beach / Beachfront
Reviewed on Jun 26, 2024
Fly From Des Moines to Panama City
Origin | Des Moines |
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Destination | Panama City |
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Cheap flights from Des Moines to Panama City
Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.
If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.
Save Even More Time and Money With a Panama City Travel Package
Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Panama City vacation that you can't get when you book flights and hotel separately.
Relax in Panama City With Confidence and Convenience
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