Cheap flights from Portland (PDX) to Knoxville (TYS)

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Lowest round trip fares by airline from Portland and Knoxville

Cheapest prices ($129 One Way, $138 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Great Deals On Cheap Hotels in Knoxville

Motel 6 Knoxville, TN

Motel 6 Knoxville, TN

2 out of 5
258 Harry Lane Blvd, Knoxville, TN
The price is $75 per night from Nov 24 to Nov 25
$75
includes taxes & fees
$64 per night
Nov 24 - Nov 25
Stay at this motel in Knoxville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
5.8/10 (1,000 reviews)
"Affordable"

Reviewed on Nov 11, 2024

Motel 6 Knoxville, TN
Red Roof Inn Knoxville Central - Papermill Road

Red Roof Inn Knoxville Central - Papermill Road

2 out of 5
1315 Kirby Rd, Knoxville, TN
The price is $75 per night from Dec 1 to Dec 2
$75
includes taxes & fees
$64 per night
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Knoxville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
6.6/10 (1,000 reviews)
"Stayed here for a football game and was very satisfied. Can’t beat it for the price"

Reviewed on Nov 11, 2024

Red Roof Inn Knoxville Central - Papermill Road
Red Roof Inn PLUS+ & Suites Knoxville West-Cedar Bluff

Red Roof Inn PLUS+ & Suites Knoxville West-Cedar Bluff

2.5 out of 5
208 Market Pl Blvd, Knoxville, TN
The price is $79 per night from Dec 2 to Dec 3
$79
includes taxes & fees
$67 per night
Dec 2 - Dec 3
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.2/10 Good! (1,002 reviews)
"Amazing!"

Reviewed on Nov 19, 2024

Red Roof Inn PLUS+ & Suites Knoxville West-Cedar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From Portland to Knoxville

Origin
Portland
Destination
Knoxville
Number of Daily Flights
Earliest Flight Departure Date
Latest Flight Departure Date
Popular Airlines

Cheap flights from Portland to Knoxville

Are you ready to book your flight, but feeling nervous about paying too much if prices drop in a few days? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus $50 more in CheapCash, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Knoxville Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Knoxville vacation that you can't get when you book flights and hotel separately.

Relax in Knoxville With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from Portland to Knoxville by signing up for exclusive email deals.

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.