Compare Cheap Seneca Independent
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Independent in Seneca

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
$123 nightly
The price is $135 total per night
$135 total
Jan 20 - Jan 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
5.27 mi from city center
With a stay at Lakeside Lodge Clemson in Seneca, you'll be a 2-minute drive from Clemson University and 10 minutes from Lake Keowee.
Pool
Hot Tub

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
$79 nightly
The price is $87 total per night
$87 total
Jan 25 - Jan 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
2.36 mi from city center
With a stay at Quality Inn Seneca Clemson Area US-123, you'll be centrally located in Seneca, a 5-minute drive from Lake Keowee and 13 minutes from Clemson University.
Pool
Breakfast included

Tru by Hilton Seneca Clemson
13050 Clemson Blvd Seneca SC
$105 nightly
The price is $115 total per night
$115 total
Jan 25 - Jan 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
5.12 mi from city center
When you stay at Tru by Hilton Seneca Clemson in Seneca, you'll be in a shopping district, within a 5-minute drive of Clemson University and Littlejohn Coliseum.
Breakfast included
Pet friendly

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$129 nightly
The price is $142 total per night
$142 total
Feb 10 - Feb 11
Total with taxes and fees
4.92 mi from city center
With a stay at Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy in Seneca, you'll be in a regional park, within a 15-minute drive of Lake Keowee and Lake Hartwell.
Kitchen
Pet friendly

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
$119 nightly
The price is $131 total per night
$131 total
Jan 25 - Jan 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.15 mi from city center
When you stay at Hampton Inn & Suites Seneca-Clemson Area in Seneca, you'll be in the business district, a 2-minute drive from Lake Keowee and 7 minutes from Clemson University.
Pool
Breakfast included

Fairfield Inn & Suites Seneca Clemson Univ Area
800 BYPASS 123 Seneca SC
$120 nightly
The price is $132 total per night
$132 total
Jan 24 - Jan 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.08 mi from city center
When you stay at Fairfield Inn & Suites Seneca Clemson Univ Area in Seneca, you'll be on a lake, a 1-minute drive from Lake Keowee and 9 minutes from Clemson University.
Pool
Breakfast included

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
$70 nightly
The price is $77 total per night
$77 total
Jan 25 - Jan 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.92 mi from city center
When you stay at Days Inn by Wyndham Seneca / Clemson Area in Seneca, you'll be in the business district, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Breakfast included

Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.
Seneca SC
2.05 mi from city center
When you stay at this vacation home in Seneca, you'll be on the waterfront, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Kitchen

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Seneca SC
10.15 mi from city center
With a stay at this vacation home in Seneca, you'll be on the waterfront, within a 10-minute drive of Lake Keowee and High Falls County Park.
Hot Tub
Kitchen

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Seneca SC
1.26 mi from city center
When you stay at this vacation home in Seneca, you'll be on the waterfront, a 1-minute drive from Lake Keowee and 9 minutes from Clemson University.
Kitchen
Washer
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.
Seneca hotels essential information
Accommodation | 1,622 hotels |
|---|---|
Lowest Price | $77 |
Highest Price | $142 |
Popular hotels | Lakeside Lodge Clemson, Quality Inn Seneca Clemson Area US-123, Tru by Hilton Seneca Clemson, Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy, Hampton Inn & Suites Seneca-Clemson Area, Fairfield Inn & Suites Seneca Clemson Univ Area , Days Inn by Wyndham Seneca / Clemson Area, Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson., Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub, Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock, 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!, 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water. |
Most Recent Seneca Hotel Reviews

Quality Inn Seneca Clemson Area US-123
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Only disappointment was no closed caption on tv"
A verified traveler stayed at Quality Inn Seneca Clemson Area US-123
Types of Hotels
Top 20 Seneca Hotels
Hotels Near Seneca
Hotels By Star Rating
Cities near Seneca
More to Explore in Seneca
Top Picks
Hotels
- Hotels in Anderson
- Hotels in North Charleston
- Hotels in Sullivan's Island
- Hotels in Clemson
- Hotels in Mount Pleasant
- Hotels in Summerville
- Hotels in Surfside Beach
- Hotels in Charleston
- Hotels in Myrtle Beach
- Hotels in Greenville
- Hotels in Pawleys Island
- Hotels in Columbia
- Hotels in Daufuskie Island
- Hotels in Kiawah Island
- Hotels in Folly Beach
- 4 Star Hotels in Myrtle Beach
- Hotels in North Myrtle Beach
Flights







