Compare Hotels with Air Conditioning in Seneca

Secret Bargains - Save an extra 10% or more on select Hotels with Air Conditioning

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Featured Seneca Hotels with Air Conditioning

Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
$89 nightly
The price is $98 total per night
$98 total
Mar 1 - Mar 2
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Best Western Seneca-Clemson in Seneca, you'll be a 1-minute drive from Lake Keowee and 8 minutes from Clemson University.
Pool
Breakfast included
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca SC
With a stay at this cabin in Seneca, you'll be in the mountains, within a 15-minute drive of Lake Keowee and Golden Corner Plaza.
Kitchen
Washer
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
$71 nightly
The price is $79 total per night
$79 total
Mar 3 - Mar 4
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Days Inn by Wyndham Seneca / Clemson Area in Seneca, you'll be in the business district, within a 15-minute drive of Lake Keowee and Clemson University.
Pool
Breakfast included
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
$121 nightly
The price is $133 total per night
$133 total
Mar 8 - Mar 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hampton Inn & Suites Seneca-Clemson Area in Seneca, you'll be in the business district, a 2-minute drive from Lake Keowee and 7 minutes from Clemson University.
Pool
Breakfast included
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca SC
Located in Seneca, this vacation home is on the waterfront, within a 15-minute drive of Lake Hartwell and Friendship Recreaction Area.
Pool
Kitchen
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
$84 nightly
The price is $92 total per night
$92 total
Feb 28 - Mar 1
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Quality Inn Seneca Clemson Area US-123, you'll be centrally located in Seneca, a 3-minute drive from Lake Keowee and 10 minutes from Clemson University.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Seneca hotels essential information

Accommodation
1,642 hotels
Lowest Price
$79
Highest Price
$133
Popular hotels
Best Western Seneca-Clemson, Fall fun at the cabin! Convenient to Lake Keowee and Clemson, Days Inn by Wyndham Seneca / Clemson Area, Hampton Inn & Suites Seneca-Clemson Area, 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks, Quality Inn Seneca Clemson Area US-123

Most Recent Seneca Hotel Reviews

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

5 out of 5
Posted 4 days ago
CheapTickets Verified Review
"I have been more then once to this location and cabins are spotless, always stocked with snacks. The staff always friendly and welcoming and my dog Sammy a shepard mix enjoys the stays as well. See you next time."
A verified traveler stayed at Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Types of Hotels

Top 20 Seneca Hotels

Hotels Near Seneca

Top Hotel Brands

Hotels By Star Rating

Cities near Seneca