James Island Vacation Rentals

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Vacation Rentals in James Island

Don't see what you're looking for?
See all available properties in James Island
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

James Island Vacation Rentals essential information

Accommodation
1070 Vacation Rentals
Lowest Price
$327
Highest Price
$897
Popular accommodation
Location + Luxury 3BD/3BA - 2 Blocks to King!, Charleston Home w/ Rooftop Deck!, Downtown Three Story Home • Walk to King Street!, Cozy and Spacious Condo: Prime Location, Minutes from Beach and Downtown!, Turtle Bay 15 - Riverfront - Dock & Pool, Charming Pet Friendly Oceanview Bungalow - Prime Location - Steps to beach, TREEHOUSE AT THE BEACH-NEW Heated Pool-1 Block to Beach & 1 Block to Wild Dunes, Beautiful Isle of Palms home with heated spa and private pool! Close to beach!, Southern sophistication in Honey Ridge, Exclusive, safe, quiet island living Charleston!, ✰ ZUMA SUITE ✰ Walk to King Street Shops!, 2 Blocks to King St - 2 Bedroom/3 Bath, Sleeps 6!