Compare Cheap Hotels in Cairo

Secret Bargains - Save an extra 10% or more on select hotels

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Cheap Cairo Hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
$68 nightly
The price is $75 total per night
$75 total
Mar 6 - Mar 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
2.68 mi from city center
With a stay at Quality Inn Cairo I-57 in Cairo, you'll be within a 15-minute drive of Mississippi River and Ohio River Valley.
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
$62 nightly
The price is $69 total per night
$69 total
Mar 26 - Mar 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.04 mi from city center
With a stay at Super 8 by Wyndham Charleston/Sikeston East MO, you'll be centrally located in Charleston, 10.3 mi (16.6 km) from Mississippi River and 20.5 mi (33 km) from Shawnee National Forest.
Breakfast included
Pet friendly
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
$173 nightly
The price is $183 total per night
$183 total
Feb 25 - Feb 26
Total with taxes and fees
10.85 mi from city center
This cabin is 0.3 mi (0.4 km) from Shawnee National Forest and 6.2 mi (9.9 km) from Ohio River Valley.
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL
$133 nightly
The price is $140 total per night
$140 total
Mar 1 - Mar 2
Total with taxes and fees
14.88 mi from city center
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
The Rested Duck Mallard Room

The Rested Duck Mallard Room

Olive Branch IL
$133 nightly
The price is $140 total per night
$140 total
Mar 1 - Mar 2
Total with taxes and fees
14.88 mi from city center
This cabin is 0.4 mi (0.7 km) from Shawnee National Forest and 5.2 mi (8.4 km) from Mississippi River.
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St Charleston MO
$70 nightly
The price is $78 total per night
$78 total
Mar 26 - Mar 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.71 mi from city center
When you stay at The Riverstone Hotel Charleston-Sikeston in Charleston, you'll be 13 minutes by car from City of Miner Convention Center.
La Center Motel

La Center Motel

2 out of 5
474 W Kentucky Dr La Center KY
Free Cancellation
Reserve now, pay when you stay
11.79 mi from city center
When you stay at La Center Motel in La Center, you'll be 13 minutes by car from Ohio River Valley.
Parking included
Free WiFi
Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

Dongola IL
$265 nightly
The price is $281 total per night
$281 total
Feb 26 - Feb 27
Total with taxes and fees
24.79 mi from city center
Located in Dongola, this cabin is on a lake, within a 15-minute drive of Dongola Lake and Dongola Public Library.
Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.

2 out of 5
Tamms IL
17.4 mi from city center
When you stay at this vacation home in Tamms, you'll be 1 minutes by foot from Shawnee National Forest.
Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall

Kevil KY
18.71 mi from city center
With a stay at this vacation home in Kevil, you'll be within a 15-minute drive of Ohio River Valley and Paul Rowton Indoor Tennis Center.
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Kevil KY
17.75 mi from city center
With a stay at this vacation home in Kevil, you'll be 16.8 mi (27.1 km) from Mississippi River and 27 mi (43.4 km) from Shawnee National Forest.
Beautiful Cabin Retreat

Beautiful Cabin Retreat

tamms IL
21.95 mi from city center
With a stay at this lodge in Tamms, you'll be in the mountains, within a 15-minute drive of Shawnee National Forest and Ullin City Hall.
Don't see what you're looking for?
See all available properties in Cairo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cairo hotels essential information

Accommodation
27 hotels
Lowest Price
$69
Highest Price
$281
Popular hotels
Quality Inn Cairo I-57, Super 8 by Wyndham Charleston/Sikeston East MO, Peaceful secluded cabin located near Horseshoe Lake , Cozy cabins on beautiful Horseshoe Lake, The Rested Duck Mallard Room, Quality Inn Charleston - Sikeston, La Center Motel, Charming cottage overlooking Lake Acre, Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout., Charming Home just minutes from Interstate and Mall, Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286, Beautiful Cabin Retreat

Most Recent Cairo Hotel Reviews

Quality Inn Cairo I-57

Quality Inn Cairo I-57

5 out of 5
Posted 2 weeks ago
CheapTickets Verified Review
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
A verified traveler stayed at Quality Inn Cairo I-57
Quality Inn Cairo I-57