Cheap flights from Santo Domingo (SDQ) to Panama City (PTY)

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Lowest round trip fares by airline from Santo Domingo and Panama City

Cheapest prices ($208 One Way, $464 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Great Deals On Cheap Hotels in Panama City

Metro Hotel Panama

Metro Hotel Panama

3.5 out of 5
Via Veneto, Calle D El Cangrejo, Panama City, Panama
The price is $46 per night from Dec 4 to Dec 5
$46
includes taxes & fees
$41 per night
Dec 4 - Dec 5
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Albrook Shopping ...
7.6/10 Good! (394 reviews)
"The best is the staff. Very professional and corteus"

Reviewed on Sep 30, 2024

Metro Hotel Panama
Hotel Centroamericano

Hotel Centroamericano

3 out of 5
Avenida Ecuador y Justo Arosemena, Zona 3, Panama City, Panama
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Popular attractions Albrook Shopping Mall and Cinta ...
7.4/10 Good! (523 reviews)
"Very clean. Good price. Good wifi and AC. Good view."

Reviewed on Mar 7, 2020

Hotel Centroamericano
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 out of 5
Calle 53 Marbella y Avenida 5a B sur, World Trade Center building, Panama City, Panama
The price is $72 per night from Nov 28 to Nov 29
$72
includes taxes & fees
$66 per night
Nov 28 - Nov 29
Stay at this 3.5-star hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the overall value ...
7.6/10 Good! (346 reviews)
"Our stay at the Hospedium exceeded our expectations. Would definitely go back! We enjoyed it breakfast buffet every morning."

Reviewed on Nov 11, 2024

Hospedium Princess Hotel Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From Santo Domingo to Panama City

Origin
Santo Domingo
Destination
Panama City
Number of Daily Flights
9
Earliest Flight Departure Date
Nov 28
Latest Flight Departure Date
Nov 28
Popular Airlines

Cheap flights from Santo Domingo to Panama City

Are you ready to book your flight, but feeling nervous about paying too much if prices drop in a few days? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus $50 more in CheapCash, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Panama City Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Panama City vacation that you can't get when you book flights and hotel separately.

Relax in Panama City With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.