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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Restaurant
Massages
Exterior
Exterior
Bar (on property)

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
$173
$148 nightly
$173 total
Total with taxes and fees
Feb 9 - Feb 10

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, City Museum
    ‪5 min walk‬
  • Place, St. Louis Union Station
    ‪8 min walk‬
  • Place, Enterprise Center
    ‪8 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(82 reviews)
  • 309 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout drapes

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)
  • 423 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

In-room safe, desk, laptop workspace, blackout drapes

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 237 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Loft, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout drapes

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)
  • 431 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, Accessible (Accessible)

  • 269 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (21C)

  • 1119 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Library)

  • 732 sq ft
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout drapes

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 549 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 Double Bed, Accessible

  • 388 sq ft
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Suite, 1 Double Bed, Accessible

  • 517 sq ft
  • Sleeps 2
  • 1 Double Bed

Similar properties

Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
  • Pet friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.4 out of 5, Excellent, 1,206 reviews
$97 nightly
The price is $115
Jan 25 - Jan 26
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

About the neighborhood

St. Louis

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of St. Louis Union Station and City Museum. .This luxury hotel is 0.4 mi (0.7 km) from Enterprise Center and 0.7 mi (1.1 km) from America's Center Convention Complex.

What's nearby

  • Washington Avenue Historic District - 2 min walk - 0.1 miles
  • City Museum - 5 min walk - 0.3 miles
  • St. Louis Union Station - 8 min walk - 0.4 miles
  • Enterprise Center - 8 min walk - 0.5 miles
  • St. Louis Aquarium at Union Station - 11 min walk - 0.6 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 24 min drive

Restaurants

  • ‪White Knight Diner - ‬4 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪Idol Wolf - ‬1 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.
Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.
Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.
Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1119 out of 1565 reviews
Rating 8 - Good. 237 out of 1565 reviews
Rating 6 - Okay. 107 out of 1565 reviews
Rating 4 - Poor. 47 out of 1565 reviews
Rating 2 - Terrible. 55 out of 1565 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

Reviews

10/10 Excellent

Jonathan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Neat place that is a different than you average hotel. Fun experience.
Stayed 1 night in Oct 2025

10/10 Excellent

Peter

Stayed 2 nights in Sep 2025

8/10 Good

Catricia

Stayed 1 night in Oct 2025

10/10 Excellent

Vincent

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was very kind and eager to help. Valet were quick, friendly, but very expensive considering it is not covered parking where they park the cars. The breakfast place was a joke on service, took an hour for an order and blamed a single cook in the back but thats poor management and should keep to yourself. The hotel itself was clean and had a great atmosphere. The art was great. Room AC worked well and the cleaning crew were efficient and tidy. Good distance from some major attractions although the time for walking distance to some are greatly underestimated, unless you are running to the Arch or Union Station.
Stayed 2 nights in Oct 2025

10/10 Excellent

michael

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique hotel and very convenient to City Museum.
Stayed 2 nights in Oct 2025

10/10 Excellent

Mianfeng

Liked: Cleanliness
Stayed 1 night in Aug 2025

6/10 Okay

Pamela, Leawood

Traveled with partner
Hotel could be deserving 4 star iF.. entry was vacuumed during our multiple day stay more than 1 coffee cup and only2 towels in bathroom , replaced burnt out lightbulbs in room, fresh pastries ( they were a day old according to staff) , etc. Just not managed well.
Stayed 2 nights in Oct 2025

10/10 Excellent

KEVIN

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Lora

Stayed 1 night in Oct 2025

10/10 Excellent

Lyndsey

Stayed 1 night in Oct 2025

8/10 Good

Melissa

Traveled with family
Liked: Cleanliness
Some things missing from room and we called the front desk but they never showed up. The air conditioner was very loud and kept us up. The pool area was great but out of towels.
Stayed 1 night in Oct 2025

10/10 Excellent

Tiffany

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful space, unique atmosphere and very clean.
Stayed 1 night in Oct 2025

6/10 Okay

Royal

Traveled with partner
Liked: Staff & service, amenities, property conditions & facilities
Disliked: Cleanliness
We had doubts our room had been cleaned. The shower had large globs of hair on the walls. The rest of the bathroom also left question marks, I flushed toilet, hair on counter and in sink. We were in a rush and didn’t have time to address concerns with staff before our event. We just avoided the bathroom when we returned.
Stayed 1 night in Oct 2025

10/10 Excellent

Sonali

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Lovely place
Stayed 2 nights in Oct 2025

10/10 Excellent

Timothy

Stayed 1 night in Oct 2025

10/10 Excellent

Michelle

Stayed 1 night in Oct 2025

10/10 Excellent

Kevin

Stayed 1 night in Oct 2025

4/10 Poor

Hillary

Liked: Cleanliness
Disliked: Staff & service, property conditions & facilities, room comfort
A/C was disabled in our room. Staff didn’t seem to care after asking twice. We forgot items in our room and no one will assist to get them back to us. Beautiful hotel should have amazing hospitality. Hospitality was not present at all within the hotel.
Stayed 2 nights in Oct 2025

6/10 Okay

Hillary

Disliked: Staff & service
IdolWolf bar & restaurant is perfect. Beautiful menus for dinner, brunch & cocktails. Upon arrival at the hotel, knew it wasn’t realistic for early check in. We were told $65 for early check in, we were fine with that. Checked our luggage with their 3rd party valet service, we had an appointment scheduled that we needed to leave for. When we came back later that evening, we were able to get checked in and move our luggage to the room. The next day we were unpacking and came to find that we were missing almost $500 in cash. This beautiful hotel that we had a wonderful stay in back in June, we were beyond disappointed. We raised the issue with the staff. They rerouted us to the 3rd party valet. They did take care of a the valet charges, but nothing else came to fruition to make us whole on what was stolen from us. We followed up at checkout and they upgraded us to a suite for when we check back in the next day. We did need to book a different room due to no availability for one night. We checked back in, and when we arrived to our room, the a/c was completely disabled, it was broken. We called the front desk twice that day asking for it to be fixed. We were told that they were full and couldn’t move us. We checked out, followed up on the stolen cash. Reminded them to fix the a/c. We forgot some items in a drawer. We called and was told they’ll check with housekeeping. I called the manager. No return call. We just want our items returned to us. We are happy to pay shipping.
Stayed 5 nights in Oct 2025

10/10 Excellent

Joel

Stayed 1 night in Oct 2025

10/10 Excellent

Vicki

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Oct 2025

10/10 Excellent

Jemma

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My stay there was great. The staff were so friendly and accommodating.
Stayed 1 night in Oct 2025

10/10 Excellent

anthony

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love the 21C. I try staying here every time I’m in St. Louis. There’s a great restaurant, a full art gallery and a steam room / gym as well. The staff is always super accommodating.
Stayed 1 night in Oct 2025

8/10 Good

Alex

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The room was clean and spacious. However, the information is not accurate—you need to pay additional $50 for parking.
Stayed 1 night in Sep 2025

10/10 Excellent

Rachel

Stayed 1 night in Sep 2025