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Cheap Mill Creek Hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.13 mi from city center
With a stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Hot Tub
The Riverview
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night
$109 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.65 mi from city center
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Isle Casino Cape Girardeau.
Parking included
Free WiFi
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
$116 nightly
The price is $131 total per night
$131 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
15.02 mi from city center
Located in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Shawnee National Forest and eDen Spa & Salon.
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night
$102 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.28 mi from city center
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Hot Tub
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
$70 nightly
The price is $84 total per night
$84 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
17.9 mi from city center
With a stay at Candlewood Suites Cape Girardeau by IHG in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Pet friendly
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$95 nightly
The price is $107 total per night
$107 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
18 mi from city center
With a stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.95 mi from city center
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pet friendly
Free WiFi
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$70 nightly
The price is $79 total per night
$79 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.23 mi from city center
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd Cape Girardeau MO
$99 nightly
The price is $112 total per night
$112 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.93 mi from city center
With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Pool
Breakfast included
Quality Inn
2011 North Kingshighway Cape Girardeau MO
$60 nightly
The price is $67 total per night
$67 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
18.05 mi from city center
With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Healthcare System.
Fairfield Inn & Suites by Marriott Cape Girardeau
433 CAPE WEST CROSSINGS Cape Girardeau MO
$88 nightly
The price is $99 total per night
$99 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.94 mi from city center
With a stay at Fairfield Inn & Suites by Marriott Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Mississippi River and Saint Francis Medical Center.
Hotel 7 Inn Anna
100 Richview Dr Anna IL
$90 nightly
The price is $104 total per night
$104 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
8.68 mi from city center
Located in Anna, Hotel 7 Inn Anna is within a 5-minute drive of Shawnee Community College and Anna City Park.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Mill Creek hotels essential information
Accommodation | 156 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $131 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, Courtyard by Marriott Cape Girardeau Downtown, Drury Inn & Suites Cape Girardeau, Candlewood Suites Cape Girardeau by IHG, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Pear Tree Inn Cape Girardeau Near the Medical Center, Pear Tree Inn Cape Girardeau West, Hampton Inn Cape Girardeau I 55 East, Quality Inn, Fairfield Inn & Suites by Marriott Cape Girardeau, Hotel 7 Inn Anna |
Most Recent Mill Creek Hotel Reviews
Drury Inn & Suites Cape Girardeau
5 out of 5
Posted 4 days ago
CheapTickets Verified Review
"Yes"
A verified traveler stayed at Drury Inn & Suites Cape Girardeau
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