See all 242 hotels in Jackson
- Drury Inn & Suites Jackson MO
- Comfort Suites Jackson-Cape Girardeau
- Town House Inn
- Drury Plaza Hotel Cape Girardeau Conference Center
- The Riverview
- Drury Inn & Suites Cape Girardeau
- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Quality Inn
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Holiday Inn Express & Suites Perryville by IHG
- Tru By Hilton Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East
- Days Inn by Wyndham Perryville
- Super 8 by Wyndham Perryville
- Hotel 7 Inn Anna
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Makanda Inn
- Charming farmhouse on a beautiful horse ranch-Shawnee Hills Wine Trail
- EC Reed's Mercantile and Hotel
- Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
- Rockwood Inn
- Quality Inn Perryville I-55
- The Weber Farm - Enjoy a beautiful 100 acre farm!
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
- Stunning 8-bedroom barndo on a 24-acre farm with pond
- Giant City Lodge
- Beautiful Cabin Retreat
- Outdoorsman Paradise
- Beautifully Renovated Farmhouse in Jackson, MO
- Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks
- Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks
- Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau
- The Mediterranean House 1858